Cardiac Purkinje cells

被引：67

作者：

Boyden, Penelope A. ^{[1
]}

Hirose, Masanori ^{[2
]}

Dun, Wen ^{[1
]}

机构：

[1] Columbia Univ, Dept Pharmacol, Columbia Coll Phys & Surg, Ctr Mol Therapeut, New York, NY 10032 USA

[2] Tohoku Univ, Sch Med, Dept Cardiol, Sendai, Miyagi 980, Japan

来源：

HEART RHYTHM | 2010年 / 7卷 / 01期

关键词：

Arrhythmia; Calcium; Ion channel; Pacemaker activity; Purkinje cell; EARLY AFTERDEPOLARIZATIONS; VENTRICULAR-TACHYCARDIA; CA2+ RELEASE; INTRACELLULAR CA-2; CALCIUM TRANSIENTS; CATHETER ABLATION; LONG-QT; FIBERS; HEART; FIBRILLATION;

D O I：

10.1016/j.hrthm.2009.09.017

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Purkinje cells are specialized for rapid propagation in the heart. Furthermore, Purkinje fibers as the source as well as the perpetuator of arrhythmias is a familiar finding. This is not surprising considering their location in the heart and their unique cell ultrastructure, cell electrophysiology, and mode of excitation-contraction coupling. This review touches on each of these points as we outline what is known today about Purkinje fibers/cells.

引用

页码：127 / 135

页数：9

共 72 条

[1]

ABIGERGES N, 2005, BRIT J PHARMACOL, V147, P653

[2] EHRA/HRS Expert Consensus on Catheter Ablation of Ventricular Arrhythmias [J].

Aliot, Etienne M. ;

Stevenson, William G. ;

Ma Almendral-Garrote, Jesus ;

Bogun, Frank ;

Calkins, C. Hugh ;

Delacretaz, Etienne ;

Della Bella, Paolo ;

Hindricks, Gerhard ;

Jais, Pierre ;

Josephson, Mark E. ;

Kautzner, Josef ;

Kay, G. Neal ;

Kuck, Karl-Heinz ;

Lerman, Bruce B. ;

Marchlinski, Francis ;

Reddy, Vivek ;

Schalij, Martin-Jan ;

Schilling, Richard ;

Soejima, Kyoko ;

Wilber, David .

HEART RHYTHM, 2009, 6 (06) :886-933

[3] Role of Purkinje fibers in post-infarction ventricular tachycardia [J].

Bogun, Frank ;

Good, Eric ;

Reich, Stephen ;

Elmouchi, Darryl ;

Igic, Petar ;

Tschopp, David ;

Dey, Sujoya ;

Wimmer, Alan ;

Jongnarangsin, Krit ;

Oral, Hakan ;

Chugh, Aman ;

Pelosi, Frank ;

Morady, Fred .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2006, 48 (12) :2500-2507

[4] Ca2+ transients and Ca2+ waves in Purkinje cells -: Role in action potential initiation [J].

Boyden, PA ;

Pu, JL ;

Pinto, J ;

ter Keurs, HEDJ .

CIRCULATION RESEARCH, 2000, 86 (04) :448-455

[5] 2APB- and JTV519(K201)-sensitive micro Ca2+ waves in arrhythmogenic Purkinje cells that survive in infarcted canine heart [J].

Boyden, PA ;

Dun, W ;

Barbhaiya, C ;

ter Keurs, HEDJ .

HEART RHYTHM, 2004, 1 (02) :218-226

[6] Nonuniform Ca2+ transients in arrhythmogenic Purkinje cells that survive in the infarcted canine heart [J].

Boyden, PA ;

Barbhaiya, C ;

Lee, T ;

ter Keurs, HEDJ .

CARDIOVASCULAR RESEARCH, 2003, 57 (03) :681-693

[7] REDUCED CALCIUM CURRENTS IN SUBENDOCARDIAL PURKINJE MYOCYTES THAT SURVIVE IN THE 24-HOUR AND 48-HOUR INFARCTED HEART [J].

BOYDEN, PA ;

PINTO, JMB .

CIRCULATION, 1994, 89 (06) :2747-2759

[8] ELECTROPHYSIOLOGY AND ULTRASTRUCTURE OF CANINE SUBENDOCARDIAL PURKINJE-CELLS ISOLATED FROM CONTROL AND 24-HOUR INFARCTED HEARTS [J].

BOYDEN, PA ;

ALBALA, A ;

DRESDNER, KP .

CIRCULATION RESEARCH, 1989, 65 (04) :955-970

[9] Reinduction of atrial fibrillation immediately after termination of the arrhythmia is mediated by late phase 3 early afterdepolarization-induced triggered activity [J].

Burashnikov, A ;

Antzelevitch, C .

CIRCULATION, 2003, 107 (18) :2355-2360

[10] SINGLE CARDIAC PURKINJE-CELLS - GENERAL ELECTROPHYSIOLOGY AND VOLTAGE-CLAMP ANALYSIS OF THE PACE-MAKER CURRENT [J].

CALLEWAERT, G ;

CARMELIET, E ;

VEREECKE, J .

JOURNAL OF PHYSIOLOGY-LONDON, 1984, 349 (APR) :643-&

← 1 2 3 4 5 6 7 8 →