Reproducibility of blood flow and post-occlusive reactive hyperaemia as measured by venous occlusion plethysmography

被引:62
作者
Thijssen, DHJ
Bleeker, MWP
Smits, P
Hopman, MTE
机构
[1] Radboud Univ Nijmegen, Med Ctr, Dept Physiol, NL-6500 HB Nijmegen, Netherlands
[2] Radboud Univ Nijmegen, Nijmegen Med Ctr, Dept Pharmacol & Toxicol, NL-6500 HB Nijmegen, Netherlands
关键词
blood flow; variability; vascular resistance; venous occlusion plethysmography;
D O I
10.1042/CS20040177
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Venous occlusion plethysmography is commonly used as a tool to assess BF (blood flow) and VIR (vascular resistance) at baseline and during PORH (post-occlusive reactive hyperaemia). However, little is known about the reproducibility of this method. The purpose of the present study was to investigate short- (hours) and medium (week)-term reproducibility of forearm, calf and thigh BF and VR at baseline and during PORH. Reproducibility was assessed by the CV (coefficient of variation). In eight subjects, baseline BF and VR of the forearm, calf and thigh were measured using venous occlusion plethysmography (50 mmHg). PORH and minimal VR were measured after 13 min of arterial occlusion (220 mmHg). Reproducibility of baseline forearm and calf BF was acceptable and in agreement with previous studies (CV, 12.9-21.2%). Short- and medium-term reproducibility of thigh BF was good (CV, 5.9% and 8.7% respectively). Baseline VIR showed acceptable-to-good reproducibility for forearm, calf and thigh (8.3-22.5%). Forearm PORH showed a CV of 6.1% (short term) and 8.6% (medium term); this was 6.1% (short term) and 6.4% (medium term) for the calf and 6.4% (short term) and 8.0% (medium term) for the thigh. Minimal VR showed good-to-acceptable reproducibility (CY, 6.1-11.7%). In conclusion, forearm, calf and thigh BF and PORH measured by plethysmography have an acceptable-to-good short- and medium-term reproducibility. Short- and medium-term reproducibility of forearm and calf baseline BF are acceptable and thigh baseline BF has a good short- and medium-term reproducibility. Therefore plethysmography is a suitable low-cost tool to assess thigh baseline BF and PORH.
引用
收藏
页码:151 / 157
页数:7
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