Expression of Hex mRNA in early murine postimplantation embryo development

被引：49

作者：

Keng, VW

Fujimori, KE

Myint, Z

Tamamaki, N

Nojyo, Y

Noguchi, T ^{[1
]}

机构：

[1] Fukui Med Univ, Dept Biochem, Fukui 9101193, Japan

[2] Fukui Med Univ, Dept Anat, Fukui 9101193, Japan

来源：

FEBS LETTERS | 1998年 / 426卷 / 02期

关键词：

Hex; liver; thyroid; lung; in situ hybridization; murine embryo;

D O I：

10.1016/S0014-5793(98)00342-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The onset of Hex expression and its role in early murine development was analyzed using in situ hybridization, Hex mRNA was first detected in the chorion of the ectoplacental cavity and weakly at the visceral endoderm of the future yolk sac at embryonic age (E) 7.5. Expression in embryonic tissues was detected exclusively in the hepatic anlage and thyroid primordium at E 9.5. At E 12.5 and E 15.5, Hex expression persisted in the fetal liver and thyroid, and was also detected in the fetal lung. These results suggest that Hex has its role in differentiation and/or organogenesis of several embryonic tissues. (C) 1998 Federation of European Biochemical Societies.

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页码：183 / 186

页数：4

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