Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens

被引：77

作者：

Buckley, Alan

Dawson, Alistair

Gould, Ernest A.

机构：

[1] CEH Oxford, Oxford OX1 3SR, England

[2] CEH Monks Wood, Huntingdon PE28 2LS, Cambs, England

来源：

VIROLOGY JOURNAL | 2006年 / 3卷 / 1期

关键词：

D O I：

10.1186/1743-422X-3-71

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We previously reported evidence of West Nile virus (WNV) circulation in UK birds, probably introduced by migratory birds from overseas. We now demonstrate WNV-specific seroconversion in sentinel chickens raised on an English farm. Maternal neutralizing antibodies to WNV in hatchlings declined within three weeks. During the following months, healthy chickens developed WNV neutralizing antibodies that were confirmed by immunoblotting and indirect immunofluorescence tests using WNV antigens. The proportion of seropositive chickens was higher for WNV than for Usutu virus or Sindbis virus. Attempts to isolate infectious virus or to detect viral RNA in the sera, failed.

引用

页数：6

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