Antimicrobial pharmacodynamics

被引:20
作者
Ambrose, PG
Owens, RC
Grasela, D
机构
[1] Univ Pacific, Sch Pharm, Stockton, CA 95211 USA
[2] Kendle Int Inc, Princeton, NJ USA
[3] Maine Med Ctr, Dept Infect Dis, Portland, ME 04102 USA
[4] Univ Vermont, Coll Med, Burlington, VT USA
[5] Bristol Myers Squibb Co, Dept Clin Pharmacol, Princeton, NJ USA
关键词
D O I
10.1016/S0025-7125(05)70296-0
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Pharmacodynamics is a science that integrates microbiological and pharmacokinetic data into more clinically relevant relationships. An understanding of pharmacodynamic concepts is essential for the clinician, for it forms the scientific basis for rational antimicrobial chemotherapy. Herein, fundamental pharmacodynamic principles and their application to clinical practice are discussed.
引用
收藏
页码:1431 / +
页数:17
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