Base excision repair enzyme family portrait: integrating the structure and chemistry of an entire DNA repair pathway

被引：86

作者：

Parikh, SS ^{[1
]}

Mol, CD ^{[1
]}

Tainer, JA ^{[1
]}

机构：

[1] Scripps Res Inst, Dept Mol Biol MB4, La Jolla, CA 92037 USA

来源：

STRUCTURE | 1997年 / 5卷 / 12期

关键词：

D O I：

10.1016/S0969-2126(97)00303-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

DNA base excision repair (EER) is essential to preserving the integrity of the genome. Recent crystallographic studies of representatives from each enzyme class required for EER reveal clues to the structural basis of an entire DNA repair pathway.

引用

页码：1543 / 1550

页数：8

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