Management of toxic epidermal necrolysis

被引：10

作者：

Craven, NM ^{[1
]}

机构：

[1] Hope Hosp, Dermatol Ctr, Salford M6 8HD, Lancs, England

来源：

HOSPITAL MEDICINE | 2000年 / 61卷 / 11期

关键词：

D O I：

10.12968/hosp.2000.61.11.1463

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Toxic epidermal necrolysis and Stevens-Johnson syndrome are rare, life-threatening drug reactions. Widespread epidermal necrosis and mucosal erosions lead to complications similar to those developing after extensive burns. Treatment is supportive. The role of steroids and other potential disease-modifying agents remains to be established by controlled studies.

引用

页码：778 / 781

页数：4

共 24 条

[1]

Arévalo JM, 2000, J TRAUMA, V48, P473

[2] ERYTHEMA MULTIFORME WITH MUCOUS-MEMBRANE INVOLVEMENT AND STEVENS-JOHNSON SYNDROME ARE CLINICALLY DIFFERENT DISORDERS WITH DISTINCT CAUSES [J].

ASSIER, H ;

BASTUJIGARIN, S ;

REVUZ, J ;

ROUJEAU, JC .

ARCHIVES OF DERMATOLOGY, 1995, 131 (05) :539-543

[3] CLINICAL CLASSIFICATION OF CASES OF TOXIC EPIDERMAL NECROLYSIS, STEVENS-JOHNSON SYNDROME, AND ERYTHEMA MULTIFORME [J].

BASTUJIGARIN, S ;

RZANY, B ;

STERN, RS ;

SHEAR, NH ;

NALDI, L ;

ROUJEAU, JC .

ARCHIVES OF DERMATOLOGY, 1993, 129 (01) :92-96

[4] Plasmapheresis as an adjunct treatment in toxic epidermal necrolysis [J].

Egan, CA ;

Grant, WJ ;

Morris, SE ;

Saffle, JR ;

Zone, JJ .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1999, 40 (03) :458-461

[5] FAMILIAL OCCURRENCE OF STEVENS-JOHNSON SYNDROME [J].

FISCHER, PR ;

SHIGEOKA, AO .

AMERICAN JOURNAL OF DISEASES OF CHILDREN, 1983, 137 (09) :914-916

[6] INVESTIGATION OF MECHANISMS IN TOXIC EPIDERMAL NECROLYSIS INDUCED BY CARBAMAZEPINE [J].

FRIEDMANN, PS ;

STRICKLAND, I ;

PIRMOHAMED, M ;

PARK, BK .

ARCHIVES OF DERMATOLOGY, 1994, 130 (05) :598-604

[7] Toxic epidermal necrolysis and Stevens-Johnson syndrome -: Does early withdrawal of causative drugs decrease the risk of death? [J].

Garcia-Doval, I ;

LeCleach, L ;

Bocquet, H ;

Otero, XL ;

Roujeau, JC .

ARCHIVES OF DERMATOLOGY, 2000, 136 (03) :323-327

[8] CHARACTERISTICS OF TOXIC EPIDERMAL NECROLYSIS IN PATIENTS UNDERGOING LONG-TERM GLUCOCORTICOID THERAPY [J].

GUIBAL, F ;

BASTUJIGARIN, S ;

CHOSIDOW, O ;

SAIAG, P ;

REVUZ, J ;

ROUJEAU, JC .

ARCHIVES OF DERMATOLOGY, 1995, 131 (06) :669-672

[9] IMPROVED BURN CENTER SURVIVAL OF PATIENTS WITH TOXIC EPIDERMAL NECROLYSIS MANAGED WITHOUT CORTICOSTEROIDS [J].

HALEBIAN, PH ;

CORDER, VJ ;

MADDEN, MR ;

FINKLESTEIN, JL ;

SHIRES, GT .

ANNALS OF SURGERY, 1986, 204 (05) :503-512

[10] EFFICACY OF CYCLOPHOSPHAMIDE IN TOXIC EPIDERMAL NECROLYSIS - CLINICAL AND PATHOPHYSIOLOGIC ASPECTS [J].

HENG, MCY ;

ALLEN, SG .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1991, 25 (05) :778-786

← 1 2 3 →