γ-Methyl-substituted-γ-butyrolactones:: solid-phase synthesis employing a cyclisation-cleavage strategy

被引：48

作者：

Gouault, N ^{[1
]}

Cupif, JF ^{[1
]}

Sauleau, A ^{[1
]}

David, M ^{[1
]}

机构：

[1] Fac Pharm, Lab Chim Pharmaceut, UPRES Pharmacochim Mol Synth & Subst Nat, F-35043 Rennes, France

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 38期

关键词：

D O I：

10.1016/S0040-4039(00)00921-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The solid-phase synthesis of several gamma-methyl-substituted-gamma-butyrolactones using a cyclisation-cleavage reaction is reported. Chemical modifications of polymer-bound azido (2a) and iodo alcohols (2b) were realised in order to introduce additional diversity onto the lactone structure. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：7293 / 7297

页数：5

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