Immunotherapy for malignant gliomas: emphasis on strategies of active specific immunotherapy using autologous dendritic cells

被引：19

作者：

De Vleeschouwer, S

Van Gool, SW

Van Calenbergh, F

机构：

[1] Univ Hosp Gasthuisberg, Dept Neurosurg, B-3000 Louvain, Belgium

[2] Catholic Univ Louvain, Expt Immunol Lab, B-3000 Louvain, Belgium

[3] Univ Hosp Gasthuisberg Leuven, Dept Pediat, Louvain, Belgium

来源：

CHILDS NERVOUS SYSTEM | 2005年 / 21卷 / 01期

关键词：

glioblastoma multiforme; anaplastic astrocytoma; immune therapy; antigen-presenting cells; cancer vaccine;

D O I：

10.1007/s00381-004-0994-3

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Review: In this review, we discuss immunotherapy for malignant gliomas. Emphasis: The emphasis is on the novel strategy of active specific immunotherapy using dendritic cells as antigen-presenting cells, especially its theoretical concepts and advantages, specific requirements, critical issues, pre-clinical and early clinical experience. Dendritic cell vaccination is situated in the diversity of other immunotherapeutical approaches. Further discussion: Future directions, challenges, and drawbacks will be discussed.

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页码：7 / 18

页数：12

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