Two efficient methods for the conversion of camptothecin to mappicine ketone, an antiviral lead compound

被引：40

作者：

Das, B ^{[1
]}

Madhusudhan, P ^{[1
]}

Kashinatham, A ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Organ Chem Div 1, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 5-6期

关键词：

D O I：

10.1016/S0040-4039(97)10539-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two simple and efficient methods for the conversion of the naturally occurring alkaloid, camptothecin to mappicine ketone, an antiviral lead compound, have been described. The first method involved the treatment of camptothecin with borontrifluoride etherate and the second method utilised the microwave irradiation of the alkaloid. (C) 1997 Elsevier Science Ltd. All rights reserved.

引用

页码：431 / 432

页数：2

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