Solvent inclusion in form II carbamazepine

被引:66
作者
Cabeza, Aurora J. Cruz
Day, Graeme M.
Motherwell, W. D. Samuel
Jones, William
机构
[1] Univ Cambridge, Pfizer Inst Pharmaceut Mat Sci, Dept Chem, Cambridge CB2 1EW, England
[2] Cambridge Crystallog Data Ctr, Cambridge CB2 1EZ, England
关键词
D O I
10.1039/b701299c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We report on experimental and theoretical evidence for solvent inclusion in form II carbamazepine (R (3) over bar) and discuss the implications for the formation and stability of this form.
引用
收藏
页码:1600 / 1602
页数:3
相关论文
共 24 条
[1]  
*ACC INC, 2001, CER VERS 4 6
[2]  
*ACC INC, 2004, MS MOD REL 3 0 1
[3]   Prediction and observation of isostructurality induced by solvent incorporation in multicomponent crystals [J].
Cabeza, Aurora J. Cruz ;
Day, Graeme M. ;
Motherwell, W. D. Samuel ;
Jones, William .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (45) :14466-14467
[4]   Enthalpies of vaporization of organic and organometallic compounds, 1880-2002 [J].
Chickos, JS ;
Acree, WE .
JOURNAL OF PHYSICAL AND CHEMICAL REFERENCE DATA, 2003, 32 (02) :519-878
[5]   Importance of molecular shape for the overall stability of hydrogen bond motifs in the crystal structures of various carbamazepine-type drug molecules [J].
Cruz Cabeza, Aurora J. ;
Day, Graeme M. ;
Motherwell, W. D. Samuel ;
Jones, William .
CRYSTAL GROWTH & DESIGN, 2007, 7 (01) :100-107
[6]   Amide pyramidalization in carbamazepine: A flexibility problem in crystal structure prediction? [J].
Cruz Cabeza, Aurora J. ;
Day, Graeme M. ;
Motherwell, W. D. Samuel ;
Jones, William .
CRYSTAL GROWTH & DESIGN, 2006, 6 (08) :1858-1866
[7]   Crystallization of pure anhydrous polymorphs of carbamazepine by solution enhanced dispersion with supercritical fluids (SEDS™) [J].
Edwards, AD ;
Shekunov, BY ;
Kordikowski, A ;
Forbes, RT ;
York, P .
JOURNAL OF PHARMACEUTICAL SCIENCES, 2001, 90 (08) :1115-1124
[8]   Time-resolved X-ray scattering using synchrotron radiation applied to the study of a polymorphic transition in carbamazepine [J].
Edwards, AD ;
Shekunov, BY ;
Forbes, RT ;
Grossmann, JG ;
York, P .
JOURNAL OF PHARMACEUTICAL SCIENCES, 2001, 90 (08) :1106-1114
[9]   Crystal engineering of the composition of pharmaceutical phases:: Multiple-component crystalline solids involving carbamazepine [J].
Fleischman, SG ;
Kuduva, SS ;
McMahon, JA ;
Moulton, B ;
Walsh, RDB ;
Rodríguez-Hornedo, N ;
Zaworotko, MJ .
CRYSTAL GROWTH & DESIGN, 2003, 3 (06) :909-919
[10]   An automated parallel crystallisation search for predicted crystal structures and packing motifs of carbamazepine [J].
Florence, Alastair J. ;
Johnston, Andrea ;
Price, Sarah L. ;
Nowell, Harriott ;
Kennedy, Alan R. ;
Shankland, Norman .
JOURNAL OF PHARMACEUTICAL SCIENCES, 2006, 95 (09) :1918-1930