Infection with an extended-spectrum β-lactamase-producing strain of Serratia marcescens following tongue reconstruction

被引:13
作者
Dhawan, B
Bonnet, R
Shukla, NK
Mathur, P
Das, BK
Kapil, A [1 ]
机构
[1] All India Inst Med Sci, Dept Microbiol, New Delhi 29, India
[2] All India Inst Med Sci, Dept Surg Oncol, Inst Rotary Canc Hosp, New Delhi 29, India
[3] Fac Med Clermont Ferrand, Serv Bacteriol Virol, F-63001 Clermont Ferrand, France
关键词
D O I
10.1128/JCM.41.5.2233-2234.2003
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We report a case of postsurgical wound infection of polymicrobial etiology caused by Serratia marcescens and Pseudomonas aeruginosa following the use of a radial forearm free flap for oncological tongue reconstruction. S. marcescens was a producer of SHV-12 extended-spectrum P-lactamase (ESBL). This is the first report from India of this ESBL. S. marcescens and P. aeruginosa were resistant to the empirical perioperative antibiotics administered. Delay in the recognition of the type of infection and in the institution of appropriate therapy resulted in total loss of the free flap.
引用
收藏
页码:2233 / 2234
页数:2
相关论文
共 11 条
[1]   SERRATIA-MARCESCENS INFECTIONS [J].
ACAR, JF .
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 1986, 7 (05) :273-278
[2]   Novel cefotaximase (CTX-M-16) with increased catalytic efficiency due to substitution Asp-240→Gly [J].
Bonnet, R ;
Dutour, C ;
Sampaio, JLM ;
Chanal, C ;
Sirot, D ;
Labia, R ;
De Champs, C ;
Sirot, J .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (08) :2269-2275
[3]   AN ASSESSMENT OF THE NEED FOR GRAM-NEGATIVE BACTERIAL COVERAGE IN ANTIBIOTIC-PROPHYLAXIS FOR ONCOLOGICAL HEAD AND NECK-SURGERY [J].
JOHNSON, JT ;
YU, VL ;
MYERS, EN ;
WAGNER, RL .
JOURNAL OF INFECTIOUS DISEASES, 1987, 155 (02) :331-333
[4]  
JOHNSON JT, 1992, ARCH OTOLARYNGOL, V118, P488
[5]   Plasmid-mediated extended-spectrum β-lactamase (CTX-M-3 like) from India and gene association with insertion sequence ISEcp1 [J].
Karim, A ;
Poirel, L ;
Nagarajan, S ;
Nordmann, P .
FEMS MICROBIOLOGY LETTERS, 2001, 201 (02) :237-241
[6]  
Mathur P, 2002, INDIAN J MED RES, V115, P153
[7]  
NCCLS, 2000, PERF STAND ANT DISK
[8]   Survey and molecular genetics of SHV beta-lactamases in Enterobacteriaceae in Switzerland: Two novel enzymes, SHV-11 and SHV-12 [J].
NueschInderbinen, MT ;
Kayser, FH ;
Hachler, H .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1997, 41 (05) :943-949
[9]   Antimicrobial resistance with focus on beta-lactam resistance in gram-negative bacilli [J].
Pitout, JDD ;
Sanders, CC ;
Sanders, WE .
AMERICAN JOURNAL OF MEDICINE, 1997, 103 (01) :51-59
[10]   An outbreak of extended-spectrum, β-lactamase-producing Salmonella senftenberg in a burns ward [J].
Revathi, G ;
Shannon, KP ;
Stapleton, PD ;
Jain, BK ;
French, GL .
JOURNAL OF HOSPITAL INFECTION, 1998, 40 (04) :295-302