Highly oxidized cuparene-type sesquiterpenes from a mycelial culture of Flammulina velutipes

被引：113

作者：

Ishikawa, NK

Yamaji, K

Tahara, S

Fukushi, Y

Takahashi, K ^{[1
]}

机构：

[1] Hokkaido Univ, Grad Sch Agr, Div Environm Resources, Kita Ku, Sapporo, Hokkaido 0608589, Japan

[2] Hokkaido Univ, Grad Sch Agr, Div Appl Biosci, Kita Ku, Sapporo, Hokkaido 0608589, Japan

来源：

PHYTOCHEMISTRY | 2000年 / 54卷 / 08期

关键词：

Flammulina velutipes; tricolomataceae; basidiomycota; enokitake; antimicrobial activity; sesquiterpenoid; cuparene-type; enokipodin A; enokipodin B;

D O I：

10.1016/S0031-9422(00)00189-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Cuparene-type sesquiterpenes were isolated from a culture broth of Flammulina velutipes (Curt.:Fr.) Sing. Using spectroscopic methods (HR-MS,H-1 and C-13 NMR, and 2D NMR, spectroscopy), their structures were determined to be 2,3,4,5-tetrahydro-2,7-dihydroxy-5,8,10,10-tetramethyl-2,5-methano-1-benzoxepin and 5-methyl-2-(3-oxo-1,2,2-trimethylcyclopentyl)benzoquinone. Both showed antimicrobial activity against Cladosporium herbarum and Bacillus subtilis. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：777 / 782

页数：6

共 17 条

[1]

HYDROXYLAGOPODIN-B - SESQUITERPENOID QUINONE FROM A MUTANT STRAIN OF COPRINUS-MACRORHIZUS VAR MICROSPORUS [J].