Recent advances in radiotherapy

被引：104

作者：

Bhide, S. A.

Nutting, C. M. ^{[1
]}

机构：

[1] Inst Canc Res, London SW3 6JB, England

来源：

BMC MEDICINE | 2010年 / 8卷

关键词：

INTENSITY-MODULATED RADIOTHERAPY; POSITRON-EMISSION-TOMOGRAPHY; CONFORMAL RADIATION-THERAPY; LOCALIZED PROSTATE-CANCER; NECK-CANCER; COMPUTED-TOMOGRAPHY; RANDOMIZED-TRIAL; 70; GY; HEAD; TOXICITY;

D O I：

10.1186/1741-7015-8-25

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Radiation therapy has come a long way from treatment planning based on orthogonal radiographs with large margins around tumours. Advances in imaging and radiation planning software have led to three-dimensional conformal radiotherapy and, further, to intensity modulated radiotherapy (IMRT). IMRT permits sparing of normal tissues and hence dose-escalation to tumours. IMRT is the current standard in treatment of head and prostate cancer and is being investigated in other tumour sites. Exquisitely sculpted dose distributions (increased geographical miss) with IMRT, plus tumour motion and anatomical changes during radiotherapy make image guided radiotherapy an essential part of modern radiation delivery. Various hardware and software tools are under investigation for optimal IGRT.

引用

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