Medically important bacterial-fungal interactions

被引:468
作者
Peleg, Anton Y. [1 ,2 ,3 ]
Hogan, Deborah A. [4 ]
Mylonakis, Eleftherios [1 ,3 ]
机构
[1] Massachusetts Gen Hosp, Div Infect Dis, Boston, MA 02114 USA
[2] Beth Israel Deaconess Med Ctr, Boston, MA 02215 USA
[3] Harvard Univ, Sch Med, Boston, MA 02115 USA
[4] Dartmouth Med Sch, Dept Microbiol & Immunol, Hanover, NH 03755 USA
关键词
INTENSIVE-CARE UNITS; CANDIDA-ALBICANS; PSEUDOMONAS-AERUGINOSA; STAPHYLOCOCCUS-AUREUS; ACINETOBACTER-BAUMANNII; BIOFILM FORMATION; ESCHERICHIA-COLI; IN-VITRO; NOSOCOMIAL INFECTIONS; SWARMING MOTILITY;
D O I
10.1038/nrmicro2313
中图分类号
Q93 [微生物学];
学科分类号
071005 [微生物学];
摘要
Whether it is in the setting of disease or in a healthy state, the human body contains a diverse range of microorganisms, including bacteria and fungi. The interactions between these taxonomically diverse microorganisms are highly dynamic and dependent on a multitude of microorganism and host factors. Human disease can develop from an imbalance between commensal bacteria and fungi or from invasion of particular host niches by opportunistic bacterial and fungal pathogens. This Review describes the clinical and molecular characteristics of bacterial-fungal interactions that are relevant to human disease.
引用
收藏
页码:340 / 349
页数:10
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