Adult nondiarrhea hemolytic uremic syndrome associated with Shiga toxin Escherichia coli O157:H7 bacteremia and urinary tract infection -: art. no. E4

被引:25
作者
Chiurchiu, C
Firrincieli, A
Santostefano, M
Fusaroli, M
Remuzzi, G
Ruggenenti, P
机构
[1] Clin Res Ctr Rare Dis Aldo & Cele Dacco, Villa Camozzi Ranica, Italy
[2] Azienda Unita Sanit Locale Ravenna, Div Nephrol & Dialysis, Villa Camozzi, Ranica, Italy
[3] Osped Riuniti Bergamo, Azienda Osped, Unit Nephrol & Dialysis, I-24100 Bergamo, Italy
[4] Mario Negri Inst Pharmacol Res, Clin Res Ctr Rare Dis Aldo & Cele Dacco, I-24125 Bergamo, Italy
关键词
hemolytic uremic syndrome (HUS); urinary tract infection (UTI); Shiga toxin; bacteremia; antibiotic treatment;
D O I
10.1053/ajkd.2003.50022
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
About 15% of children with Shiga toxin (Stx) producing Escherichia coli (STEC) primarily of serotype O157:117, gastrointestinal infection, and watery or bloody diarrhea, may develop hemolytic uremic syndrome (D+ HUS). Usually D+ HUS is not complicated by bacteremia and patients recover spontaneously without antibiotic treatment. We report here an adult case of a STEC O157:117 urinary tract infection complicated by bacteremia and HUS that was not preceded by diarrhea (D- HUS). Cases of D- HUS need to be carefully examined for foci other than the gastrointestinal tract, and patients with E coli bacteremia should receive early antibiotic treatment as would any patient with sepsis.
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页数:4
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