Targeting effectors: the molecular recognition of Type III secreted proteins

被引：20

作者：

Arnold, Roland ^{[2
]}

Jehl, Andre ^{[2
]}

Rattei, Thomas ^{[1
,2
]}

机构：

[1] Univ Vienna, Dept Computat Syst Biol, Fac Life Sci, A-1090 Vienna, Austria

[2] Tech Univ Munich, Dept Genome Oriented Bioinformat, Wissensch Zentrum Weihenstephan, D-85350 Freising Weihenstephan, Germany

来源：

MICROBES AND INFECTION | 2010年 / 12卷 / 05期

关键词：

Type III secretion; Signal peptide; Effector proteins; DRAFT GENOME SEQUENCE; MESSENGER-RNA SIGNAL; PSEUDOMONAS-SYRINGAE; YERSINIA-ENTEROCOLITICA; IDENTIFICATION; REPERTOIRE; EXPRESSION; SYSTEM; TRANSLOCATION; CHAPERONES;

D O I：

10.1016/j.micinf.2010.02.003

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The Type III secretion system (TTSS) facilitates the export of effector proteins from pathogenic and symbiotic Gram-negative bacteria into the cytosol of eukaryotic host cells. The current functional and evolutionary knowledge on the molecular recognition of TTSS substrates and computational models of the secretion signal are discussed in this review. (C) 2010 Elsevier Masson SAS. All rights reserved.

引用

页码：346 / 358

页数：13

共 70 条

[1] Chaperone release and unfolding of substrates in type III secretion [J].

Akeda, Y ;

Galán, JE .

NATURE, 2005, 437 (7060) :911-915

[2] A Draft Genome Sequence of Pseudomonas syringae pv. tomato T1 Reveals a Type III Effector Repertoire Significantly Divergent from That of Pseudomonas syringae pv. tomato DC3000 [J].

Almeida, Nalvo F. ;

Yan, Shuangchun ;

Lindeberg, Magdalen ;

Studholme, David J. ;

Schneider, David J. ;

Condon, Bradford ;

Liu, Haijie ;

Viana, Carlos J. ;

Warren, Andrew ;

Evans, Clive ;

Kemen, Eric ;

MacLean, Dan ;

Angot, Aurelie ;

Martin, Gregory B. ;

Jones, Jonathan D. ;

Collmer, Alan ;

Setubal, Joao C. ;

Vinatzer, Boris A. .

MOLECULAR PLANT-MICROBE INTERACTIONS, 2009, 22 (01) :52-62

[3] Yersinia enterocolitica type III secretion:: an mRNA signal that couples translation and secretion of YopQ [J].

Anderson, DM ;

Schneewind, O .

MOLECULAR MICROBIOLOGY, 1999, 31 (04) :1139-1148

[4] A mRNA signal for the type III secretion of Yop proteins by Yersinia enterocolitica [J].

Anderson, DM ;

Schneewind, O .

SCIENCE, 1997, 278 (5340) :1140-1143

[5] Reciprocal secretion of proteins by the bacterial type III machines of plant and animal pathogens suggests universal recognition of mRNA targeting signals [J].

Anderson, DM ;

Fouts, DE ;

Collmer, A ;

Schneewind, O .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (22) :12839-12843

[6] Sequence-Based Prediction of Type III Secreted Proteins [J].

Arnold, Roland ;

Brandmaier, Stefan ;

Kleine, Frederick ;

Tischler, Patrick ;

Heinz, Eva ;

Behrens, Sebastian ;

Niinikoski, Antti ;

Mewes, Hans-Werner ;

Horn, Matthias ;

Rattei, Thomas .

PLOS PATHOGENS, 2009, 5 (04)

[7] Secretion of flagellin by the LEE-encoded type III secretion system of enteropathogenic Escherichia coli [J].

Badea, Luminita ;

Beatson, Scott A. ;

Kaparakis, Maria ;

Ferrero, Richard L. ;

Hartland, Elizabeth L. .

BMC MICROBIOLOGY, 2009, 9

[8]

BEECKMAN D, 2009, CURR ISSUES MOL BIOL, P17

[9] From flagellum assembly to virulence: the extended family of type III export chaperones [J].

Bennett, JCQ ;

Hughes, C .

TRENDS IN MICROBIOLOGY, 2000, 8 (05) :202-204

[10] Yersinia enterocolitica type III secretion of YopR requires a structure in its mRNA [J].

Blaylock, Bill ;

Sorg, Joseph A. ;

Schneewind, Olaf .

MOLECULAR MICROBIOLOGY, 2008, 70 (05) :1210-1222

← 1 2 3 4 5 6 7 →