The neurocognitive effects of radiation in adult low-grade glioma patients

被引:50
作者
Brown, PD
Buckner, JC
Uhm, JH
Shaw, EG
机构
[1] Mayo Clin, Div Radiat Oncol, Rochester, MN 55905 USA
[2] Mayo Clin, Div Med Oncol, Rochester, MN 55905 USA
[3] Mayo Clin, Div Neurooncol, Rochester, MN 55905 USA
[4] Wake Forest Univ, Sch Med, Dept Radiat Oncol, Winston Salem, NC 27157 USA
关键词
D O I
10.1215/S1152851702000431
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Radiotherapy is a component of the treatment regimen for the majority of patients with low-grade gliomas. Therefore, the effect of radiotherapy on the long-term cognitive performance of these patients is a major concern. This article reviews the neurocognitive effects of radiotherapy on patients with low-grade gliomas. The weight of evidence suggests only sporadic, limited neurocognitive damage from focal radiotherapy at the doses usually prescribed for low-grade gliomas.
引用
收藏
页码:161 / 167
页数:7
相关论文
共 62 条
[1]   Neuropsychologic impact of standard-dose systemic chemotherapy in long-term survivors of breast cancer and lymphoma [J].
Ahles, TA ;
Saykin, AJ ;
Furstenberg, CT ;
Cole, B ;
Mott, LA ;
Skalla, K ;
Whedon, MB ;
Bivens, S ;
Mitchell, T ;
Greenberg, ER ;
Silberfarb, PM .
JOURNAL OF CLINICAL ONCOLOGY, 2002, 20 (02) :485-493
[2]   EFFECTS OF RADIATION-THERAPY ON ADULT BRAIN-BEHAVIOR - EVIDENCE FOR A REBOUND PHENOMENON IN A PHASE-1 TRIAL [J].
ARMSTRONG, C ;
MOLLMAN, J ;
CORN, BW ;
ALAVI, J ;
GROSSMAN, M .
NEUROLOGY, 1993, 43 (10) :1961-1965
[3]   BIPHASIC PATTERNS OF MEMORY DEFICITS FOLLOWING MODERATE-DOSE PARTIAL-BRAIN IRRADIATION - NEUROPSYCHOLOGIC OUTCOME AND PROPOSED MECHANISMS [J].
ARMSTRONG, C ;
RUFFER, J ;
CORN, B ;
DEVRIES, K ;
MOLLMAN, J .
JOURNAL OF CLINICAL ONCOLOGY, 1995, 13 (09) :2263-2271
[4]   Late cognitive and radiographic changes related to radiotherapy - Initial prospective findings [J].
Armstrong, CL ;
Hunter, JV ;
Ledakis, GE ;
Cohen, B ;
Tallent, EM ;
Goldstein, BH ;
Tochner, Z ;
Lustig, R ;
Judy, KD ;
Pruitt, A ;
Mollman, JE ;
Stanczak, EM ;
Jo, MY ;
Than, TL ;
Phillips, P .
NEUROLOGY, 2002, 59 (01) :40-48
[5]  
Armstrong CL, 2000, NEUROPSY NEUROPSY BE, V13, P101
[6]  
ASAI A, 1989, CANCER-AM CANCER SOC, V63, P1962, DOI 10.1002/1097-0142(19890515)63:10<1962::AID-CNCR2820631016>3.0.CO
[7]  
2-V
[8]  
Asai A, 1987, Gan No Rinsho, V33, P753
[9]  
Bahary JP, 1996, J NEURO-ONCOL, V27, P173
[10]   Cognitive function in breast cancer patients receiving adjuvant chemotherapy [J].
Brezden, CB ;
Phillips, KA ;
Abdolell, M ;
Bunston, T ;
Tannock, IF .
JOURNAL OF CLINICAL ONCOLOGY, 2000, 18 (14) :2695-2701