Gestational surrogacy: a feasible option for patients with Rokitansky syndrome

被引:51
作者
Beski, S
Gorgy, A
Venkat, G
Craft, IL
Edmonds, K
机构
[1] London Gynaecol & Fertil Ctr, London W1N 1AF, England
[2] Chelsea & Westminster Hosp, London SW10 9NH, England
[3] Queen Charlottes & Chelsea Hosp, London W6 0XG, England
关键词
congenital absence of uterus; IVF; Rokitansky syndrome; surrogacy;
D O I
10.1093/humrep/15.11.2326
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Rokitansky syndrome is a developmental defect characterized by agenesis of the uterus and vagina but normal gonads and secondary sexual characters. It is not commonly transmitted as a dominant genetic trait. Surrogacy, which is legally and ethically accepted in the UK and other countries, has made it possible for the patients with this syndrome to have their own genetic children. Sis patients with Rokitansky syndrome underwent 11 ovarian stimulation cycles that resulted in 11 fresh and three frozen embryo transfer procedures into six prospective surrogate mothers. Both commissioning and surrogate couples were properly screened and counselled and their treatment was approved bu the clinic internal review committee (ethics committee), The treatment cycles resulted in sis clinical pregnancies (42.9% pregnancy rate per embryo transfer and 54.5% per oocyte retrieval) and three live births (21.4% per embryo transfer, 27.3% per retrieval and 50% per patient). Gestational surrogacy is a viable treatment for patients with Rokitansky syndrome. Such patients should be well informed and supported to be able to have a family using their own genetic gametes.
引用
收藏
页码:2326 / 2328
页数:3
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