Enantioselective synthesis of β-hydroxy amines and aziridines using asymmetric transfer hydrogenation of α-amido ketones

被引:40
作者
Kawamoto, A [1 ]
Wills, M [1 ]
机构
[1] Univ Warwick, Dept Chem, Coventry CV4 7AL, W Midlands, England
关键词
D O I
10.1016/S0957-4166(00)00310-4
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
A rapid, expedient and enantioselective method for the synthesis of beta-hydroxy amines and monosubstituted aziridines in up to 99% e.e., via asymmetric transfer hydrogenation of alpha-amido ketones, is described. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:3257 / 3261
页数:5
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