Site-specifically labeled metallo-oligodeoxynucleotides

被引：29

作者：

Beilstein, AE ^{[1
]}

Tierney, MT ^{[1
]}

Grinstaff, MW ^{[1
]}

机构：

[1] Duke Univ, Paul M Gross Chem Lab, Durham, NC 27708 USA

来源：

COMMENTS ON INORGANIC CHEMISTRY | 2000年 / 22卷 / 1-2期

基金：

美国国家科学基金会;

关键词：

metallo-oligodeoxynucleotides; oligodeoxynucleotides; DNA; solid-phase synthesis; metal complexes;

D O I：

10.1080/02603590008050865

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Growing interest in site-specifically labeled metallo-oligodeoxyoucleotides for diagnostic, therapeutic and mechanistic applications provides the impetus for the development of new synthetic methods that are user-friendly and amenable to large-scale production. This review describes advances in the field since the early 1980's and highlights recent solution-phase and automated solid-phase coupling procedures.

引用

页码：105 / 127

页数：23

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