Resective surgery to treat refractory status epilepticus in children with focal epileptogenesis

被引：65

作者：

Alexopoulos, A

Lachhwani, DK

Gupta, A

Kotagal, P

Harrison, AM

Bingaman, W

Wyllie, E

机构：

[1] Cleveland Clin Fdn, Sect Pediat Epilepsy & Pediat Neurol, Dept Neurol, Cleveland, OH 44195 USA

[2] Cleveland Clin Fdn, Dept Pediat Crit Care Med, Cleveland, OH 44195 USA

[3] Cleveland Clin Fdn, Dept Neurosurg, Cleveland, OH 44195 USA

来源：

NEUROLOGY | 2005年 / 64卷 / 03期

关键词：

D O I：

10.1212/01.WNL.0000150580.40019.63

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Prolonged high-dose suppressive therapy (HDST) is a mainstay in the management of refractory status epilepticus (RSE), albeit with high morbidity and mortality. The authors studied 10 patients who were carefully selected for epilepsy surgery after failing prolonged (>2 weeks) HDST. Status epilepticus was stopped acutely in all of them with no mortality and no substantial morbidity. At follow-up (median 7 months), 7 (70%) of 10 patients were seizure free, and 3 (30%) of 10 had significant improvement in their epilepsy.

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页码：567 / 570

页数：4

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