Truncated internalin A and asymptomatic Listeria monocytogenes carriage:: In vivo investigation by allelic exchange

被引：31

作者：

Olier, M ^{[1
]}

Garmyn, D ^{[1
]}

Rousseaux, S ^{[1
]}

Lemaître, JP ^{[1
]}

Piveteau, P ^{[1
]}

Guzzo, J ^{[1
]}

机构：

[1] Univ Bourgogne 1, Microbiol Lab, INRA, UMR 1232, F-21000 Dijon, France

来源：

INFECTION AND IMMUNITY | 2005年 / 73卷 / 01期

关键词：

D O I：

10.1128/IAI.73.1.644-648.2005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Allelic exchange of the region coding for the C terminus of InIA between one epidemic (with an 80-kDa InIA) and one asymptomatic (with a 47-kDa InIA) carriage Listeria monocytogenes strain confirmed the need for this region for internalin entry in vitro. Interestingly, restoration of internalin A functionality did not result in full virulence in chicken embryo assays.

引用

页码：644 / 648

页数：5

共 26 条

[1]

BOJSENMOLLER J, 1972, ACTA PATHOLOG MICROB, P1

[2] Surface proteins and the pathogenic potential of Listeria monocytogenes [J].

Cabanes, D ;

Dehoux, P ;

Dussurget, O ;

Frangeul, L ;

Cossart, P .

TRENDS IN MICROBIOLOGY, 2002, 10 (05) :238-+

[3] An outbreak of gastroenteritis and fever due to Listeria monocytogenes in milk [J].

Dalton, CB ;

Austin, CC ;

Sobel, J ;

Hayes, PS ;

Bibb, WF ;

Graves, LM ;

Swaminathan, B ;

Proctor, ME ;

Griffin, PM .

NEW ENGLAND JOURNAL OF MEDICINE, 1997, 336 (02) :100-105

[4] New aspects regarding evolution and virulence of Listeria monocytogenes revealed by comparative genomics and DNA arrays [J].

Doumith, M ;

Cazalet, C ;

Simoes, N ;

Frangeul, L ;

Jacquet, C ;

Kunst, F ;

Martin, P ;

Cossart, P ;

Glaser, P ;

Buchrieser, C .

INFECTION AND IMMUNITY, 2004, 72 (02) :1072-1083

[5]

DURST J, 1976, ZBL BAKT-INT J MED M, V234, P281

[6] Genetic markers unique to Listeria monocytogenes serotype 4b differentiate epidemic clone II (hot dog outbreak strains) from other lineages [J].

Evans, MR ;

Swaminathan, B ;

Graves, LM ;

Altermann, E ;

Klaenhammer, TR ;

Fink, RC ;

Kernodle, S ;

Kathariou, S .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2004, 70 (04) :2383-2390

[7] ENTRY OF L-MONOCYTOGENES INTO CELLS IS MEDIATED BY INTERNALIN, A REPEAT PROTEIN REMINISCENT OF SURFACE-ANTIGENS FROM GRAM-POSITIVE COCCI [J].

GAILLARD, JL ;

BERCHE, P ;

FREHEL, C ;

GOUIN, E ;

COSSART, P .

CELL, 1991, 65 (07) :1127-1141

[8] Gene fragments distinguishing an epidemic-associated strain from a virulent prototype strain of Listeria monocytogenes belong to a distinct functional subset of genes and partially cross-hybridize with other Listeria species [J].

Herd, M ;

Kocks, C .

INFECTION AND IMMUNITY, 2001, 69 (06) :3972-3979

[9] Bacterial penetration across the blood-brain barrier during the development of neonatal meningitis [J].

Huang, SH ;

Stins, MF ;

Kim, KS .

MICROBES AND INFECTION, 2000, 2 (10) :1237-1244

[10]

KAMPELMACHER EH, 1972, ZENTRALBL BAKT P INF, V221, P70

← 1 2 3 →