Proposal for a unified CCN nomenclature

被引：222

作者：

Brigstock, DR

Goldschmeding, R

Katsube, K

Lam, SCT

Lau, LF

Lyons, K

Naus, C

Perbal, B ^{[1
]}

Riser, B

Takigawa, M

Yeger, H

机构：

[1] Univ Paris 07, Lab Oncol Virale & Mol, F-75005 Paris, France

[2] Ohio State Univ, Dept Surg, Columbus, OH 43205 USA

[3] Univ Utrecht Hosp, Utrecht, Netherlands

[4] Tokyo Med & Dent Univ, Grad Sch, Tokyo 1138549, Japan

[5] Univ Illinois, Dept Pharmacol, Chicago, IL 60612 USA

[6] Univ Calif Los Angeles, Dept Mol Cell & Dev Biol, Los Angeles, CA 90095 USA

[7] Univ British Columbia, Dept Anat, Vancouver, BC V6T 1Z3, Canada

[8] Univ Paris 07, Lab Oncol Virale & Mol, F-75005 Paris, France

[9] Baxter Healthcare Corp, Div Renal, Magaw Pk, IL 60085 USA

[10] Okayama Univ, Grad Sch Med & Dent, Dept Biochem & Mol Dent, Okayama 7008525, Japan

[11] Hosp Sick Children, Dept Pediat Lab Med, Toronto, ON M5G 1XB, Canada

来源：

JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY | 2003年 / 56卷 / 02期

关键词：

D O I：

10.1136/mp.56.2.127

中图分类号：

R36 [病理学];

学科分类号：

100104 [病理学与病理生理学];

摘要：

A proposal is put forth to unify the nomenclature of the CCN family of secreted, cysteine rich regulatory proteins. In the order of their description in the literature, CCN1 (CYR61), CCN2 (CTGF), CCN3 (NOV), CCN4 (WISP-1), CCN5 (WISP-2), and CCN6 (WISP-3) constitute a family of matricellular proteins that regulate cell adhesion, migration, proliferation, survival, and differentiation, at least in part through integrin mediated mechanisms. This proposal is endorsed by the International CCN Society and will serve to eliminate confusion from the multiple names that have been given to these molecules.

引用

页码：127 / 128

页数：2

共 9 条

[1]

THE MODULAR ARCHITECTURE OF A NEW FAMILY OF GROWTH-REGULATORS RELATED TO CONNECTIVE-TISSUE GROWTH-FACTOR [J].