The Eph family receptors and ligands

被引：130

作者：

Zhou, RP ^{[1
]}

机构：

[1] Rutgers State Univ, Coll Pharm, Canc Res Lab, Piscataway, NJ 08855 USA

来源：

PHARMACOLOGY & THERAPEUTICS | 1998年 / 77卷 / 03期

基金：

美国国家科学基金会;

关键词：

Eph receptors; ephrins; axonal guidance; topographic mapping; angiogenesis;

D O I：

10.1016/S0163-7258(97)00112-5

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The Eph family is the largest of all known tyrosine kinase receptor-ligand systems, They are expressed in distinct, but overlapping, spatial and temporal patterns during embryonic development and postnatal life, and function in a variety of morphogenic events, The best known function is their role in the guidance of migration of axons and cells in the nervous system through repulsive interactions. They may also play a role in angiogenesis, tissue patterning, and tumor formation. (C) 1998 Elsevier Science Inc.

引用

页码：151 / 181

页数：31

共 182 条

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