Ligustri Lucidi Fructus as a traditional Chinese medicine: a review of its phytochemistry and pharmacology

被引：128

作者：

Gao, Liangliang ^{[1
,2
]}

Li, Chun ^{[1
,2
]}

Wang, Zhimin ^{[1
,2
]}

Liu, Xiaoqian ^{[1
,2
]}

You, Yun ^{[1
,2
]}

Wei, Hua ^{[1
,2
]}

Guo, Tao ^{[1
,2
]}

机构：

[1] China Acad Chinese Med Sci, Inst Chinese Mat Med, Beijing 100700, Peoples R China

[2] Natl Engn Lab Qual Control Technol Chinese Herbal, Beijing 100700, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2015年 / 29卷 / 06期

基金：

中国国家自然科学基金;

关键词：

Ligustri Lucidi Fructus; biological effects; phytochemistry; ACID-ENRICHED EXTRACT; OLEANOLIC ACID; ETHANOL EXTRACT; IN-VITRO; CALCIUM BALANCE; SECOIRIDOID CONSTITUENTS; OVARIECTOMIZED RATS; GENE-EXPRESSION; FEMALE RATS; FRUITS;

D O I：

10.1080/14786419.2014.954114

中图分类号：

O69 [应用化学];

学科分类号：

070301 [无机化学];

摘要：

Ligustri Lucidi Fructus (LLF) is the fruits of Ligustrum lucidum Ait. (Oleaceae). This review based on nearly 80 literary sources discusses the knowledge of chemistry and biological effects of this species. Several types of chemical constituents considered as the characteristic and active constituents from LLF were isolated including 40 triterpenoids, 48 iridoids, 10 flavones, 10 phenylethanoid glycosides and others. Various extracts and individual compounds derived from this species have been found to possess a variety of pharmacological effects, e.g. anti-tumour, hepatoprotective, immune regulating, antioxidative and anti-ageing effects, anti-inflammation and reducing hypercholesterolaemia effects and so on. The results of data analysis on the chemical, pharmacological characteristics of LLF support the view that this species has many therapeutic properties and indicate its potential as an effective herbal remedy. Finally, some suggestions for further research on chemical and pharmacological properties are given in this review. Theoretical basis was given for further exploiting and utilising LLF.

引用

页码：493 / 510

页数：18

共 78 条

[1]

Six New Secoiridoids from the Dried Fruits of Ligustrum lucidum [J].