Regulation of host cell translation by viruses and effects on cell function

被引：46

作者：

Thompson, SR ^{[1
]}

Sarnow, P ^{[1
]}

机构：

[1] Stanford Univ, Sch Med, Dept Microbiol & Immunol, Stanford, CA 94305 USA

来源：

CURRENT OPINION IN MICROBIOLOGY | 2000年 / 3卷 / 04期

关键词：

D O I：

10.1016/S1369-5274(00)00106-5

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Viruses have evolved a remarkable variety of strategies to modulate the host cell translation apparatus with the aim of optimizing viral mRNA translation and replication. Recent studies have revealed that modulation of both host and viral mRNA translation can be accomplished by selective alteration of translation factors in virus-infected cells. These findings provide new insights into the functioning of the translational apparatus in both uninfected and infected cells.

引用

页码：366 / 370

页数：5

共 36 条

[1]

Abid K, 2000, Science, V287, P1555

[2] Resistance of ribosomal protein mRNA translation to protein synthesis shutoff induced by poliovirus [J].

Cardinali, B ;

Fiore, L ;

Campioni, N ;

De Dominicis, A ;

Pierandrei-Amaldi, P .

JOURNAL OF VIROLOGY, 1999, 73 (08) :7070-7076

[3]

CARTER MS, 2000, IN PRESS TRANSLATION

[4] ISOLATION OF A CDNA CLONE DERIVED FROM A BLOOD-BORNE NON-A, NON-B VIRAL-HEPATITIS GENOME [J].

CHOO, QL ;

KUO, G ;

WEINER, AJ ;

OVERBY, LR ;

BRADLEY, DW ;

HOUGHTON, M .

SCIENCE, 1989, 244 (4902) :359-362

[5] ASSOCIATION OF A M(R)-90,000 PHOSPHOPROTEIN WITH PROTEIN-KINASE PKR IN CELLS EXHIBITING ENHANCED PHOSPHORYLATION OF TRANSLATION INITIATION-FACTOR EIF-2-ALPHA AND PREMATURE SHUTOFF OF PROTEIN-SYNTHESIS AFTER INFECTION WITH GAMMA(1)34.5(-) MUTANTS OF HERPES-SIMPLEX-VIRUS-1 [J].

CHOU, J ;

CHEN, JJ ;

GROSS, M ;

ROIZMAN, B .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (23) :10516-10520

[6] Translation elongation factor 1-alpha interacts specifically with the human immunodeficiency virus type 1 Gag polyprotein [J].

Cimarelli, A ;

Luban, J .

JOURNAL OF VIROLOGY, 1999, 73 (07) :5388-5401

[7] Hepatitis C [J].

Di Bisceglie, AM .

LANCET, 1998, 351 (9099) :351-355

[8] Hepatitis C and hepatocellular carcinoma [J].

DiBisceglie, AM .

HEPATOLOGY, 1997, 26 (03) :S34-S38

[9]

Ehrenfeld E., 1996, TRANSLATIONAL CONTRO, P549

[10]

ETCHISON D, 1982, J BIOL CHEM, V257, P4806

← 1 2 3 4 →