Differentiating adult hippocampal stem cells into neural crest derivatives

被引：26

作者：

Alexanian, AR ^{[1
]}

Sieber-Blum, M ^{[1
]}

机构：

[1] Med Coll Wisconsin, Dept Cell Biol Neurobiol & Anat, Milwaukee, WI 53226 USA

来源：

NEUROSCIENCE | 2003年 / 118卷 / 01期

关键词：

ROSA26; quail; culture; melanocyte; chondrocyte; smooth muscle cell;

D O I：

10.1016/S0306-4522(02)00994-6

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

To investigate the degree of plasticity of hippocampal neural stem cells from adult mice (mHNSC), we have analyzed their differentiation in co-culture with quail neural crest cells. In mixed culture, mHNSC give rise to several non-neuronal neural crest derivatives, including melanocytes, chondrocytes and smooth muscle cells. The data suggest that neural crest cell-derived short-range cues that are recognized across species can instruct adult mHNSC to differentiate into neural crest phenotypes. (C) 2003 IBRO. Published by Elsevier Science Ltd. All rights reserved.

引用

页码：1 / 5

页数：5

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