Ovarian Cancer, Version 2.2020

被引:479
作者
Armstrong, Deborah K. [1 ]
Alvarez, Ronald D. [2 ]
Bakkum-Gamez, Jamie N. [3 ]
Barroilhet, Lisa [4 ]
Behbakht, Kian [5 ]
Berchuck, Andrew [6 ]
Chen, Lee-may [7 ]
Cristea, Mihaela [8 ]
DeRosa, Maria
Eisenhauer, Eric L. [9 ]
Gershenson, David M. [10 ]
Gray, Heidi J. [11 ]
Grisham, Rachel [12 ]
Hakam, Ardeshir [13 ]
Jain, Angela [14 ]
Karam, Amer [15 ]
Konecny, Gottfried E. [16 ]
Leath, Charles A., III [17 ]
Liu, Joyce [18 ]
Mahdi, Haider [19 ,20 ]
Martin, Lainie [21 ]
Matei, Daniela [22 ]
McHale, Michael [23 ]
McLean, Karen [24 ]
Miller, David S. [25 ]
O'Malley, David M. [26 ,27 ]
Percac-Lima, Sanja [9 ]
Ratner, Elena [28 ]
Remmenga, Steven W. [29 ]
Vargas, Roberto [19 ,20 ]
Werner, Theresa L. [30 ]
Zsiros, Emese [31 ]
Burns, Jennifer L. [32 ]
Engh, Anita M. [32 ]
机构
[1] Sidney Kimmel Comprehens Canc Ctr Johns Hopkins, Baltimore, MD 21287 USA
[2] Vanderbilt Ingram Canc Ctr, Nashville, TN USA
[3] Mayo Clin, Canc Ctr, Rochester, MN USA
[4] Univ Wisconsin, Carbone Canc Ctr, Madison, WI USA
[5] Univ Colorado, Ctr Canc, Boulder, CO 80309 USA
[6] Duke Canc Inst, Durham, NC USA
[7] UCSF Helen Diller Family Comprehens Canc Ctr, San Francisco, CA USA
[8] City Hope Natl Med Ctr, Los Angeles, CA USA
[9] Massachusetts Gen Hosp, Ctr Canc, Boston, MA USA
[10] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
[11] Fred Hutchinson Canc Res Ctr, Seattle Canc Care Alliance, Seattle, WA USA
[12] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA
[13] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA
[14] Fox Chase Canc Ctr, 7701 Burholme Ave, Philadelphia, PA 19111 USA
[15] Stanford Canc Inst, Stanford, CA USA
[16] Univ Calif Los Angeles, Jonsson Comprehens Canc Ctr, Los Angeles, CA USA
[17] UAB, ONeal Comprehens Canc Ctr, Birmingham, AL USA
[18] Dana Farber Brigham & Womens Canc Ctr, Boston, MA USA
[19] Univ Hosp Seidman Canc Ctr, Case Comprehens Canc Ctr, Cleveland, OH USA
[20] Cleveland Clin, Taussig Canc Inst, Cleveland, OH 44106 USA
[21] Univ Penn, Abramson Canc Ctr, Philadelphia, PA 19104 USA
[22] Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Evanston, IL USA
[23] UC San Diego Moores Canc Ctr, San Diego, CA USA
[24] Univ Michigan, Rogel Canc Ctr, Ann Arbor, MI 48109 USA
[25] UT Southwestern Simmons Comprehens Canc Ctr, Dallas, TX USA
[26] Ohio State Univ, Ctr Comprehens Canc, James Canc Hosp, Columbus, OH 43210 USA
[27] Solove Res Inst, Columbus, OH USA
[28] Smilow Canc Hosp, Yale Canc Ctr, New Haven, CT USA
[29] Fred & Pamela Buffett Canc Ctr, Omaha, NE USA
[30] Univ Utah, Huntsman Canc Inst, Salt Lake City, UT USA
[31] Roswell Park Comprehens Canc Ctr, Buffalo, NY USA
[32] Natl Comprehens Canc Network, Plymouth Meeting, PA USA
来源
JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2021年 / 19卷 / 02期
关键词
ADVANCED EPITHELIAL OVARIAN; FERTILITY-SPARING SURGERY; PHASE-III TRIAL; EARLY-STAGE OVARIAN; COOPERATIVE-ONCOLOGY-GROUP; TERM-FOLLOW-UP; PRIMARY CYTOREDUCTIVE SURGERY; CARBOPLATIN PLUS PACLITAXEL; INTRAVENOUS CISPLATIN PLUS; PRIMARY PERITONEAL CANCER;
D O I
10.6004/jnccn.2021.0007
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Epithelial ovarian cancer is the leading cause of death from gyne-cologic cancer in the United States and is the country's fifth most common cause of cancer mortality in women. A major challenge in treating ovarian cancer is that most patients have advanced disease at initial diagnosis. These NCCN Guidelines discuss cancers originating in the ovary, fallopian tube, or peritoneum, as these are all managed in a similar manner. Most of the recommendations are based on data from patients with the most common subtypeshigh-grade serous and grade 2/3 endometrioid. The NCCN Guidelines also include recommendations specifically for patients with less common ovarian cancers, which in the guidelines include the following: carcinosar-coma, clear cell carcinoma, mucinous carcinoma, low-grade serous, grade 1 endometrioid, borderline epithelial, malignant sex cord-stromal, and malignant germ cell tumors. This manuscript focuses on certain aspects of primary treatment, including primary surgery, adjuvant therapy, and maintenance therapy options (including PARP inhibitors) after completion of first-line chemotherapy.
引用
收藏
页码:191 / +
页数:40
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