Design of biocompatible dendrimers with environment sensitivity

被引：50

作者：

Kojima, C ^{[1
]}

Haba, Y ^{[1
]}

Fukui, T ^{[1
]}

Kono, K ^{[1
]}

Takagishi, T ^{[1
]}

机构：

[1] Univ Osaka Prefecture, Dept Appl Mat Sci, Grad Sch Engn, Sakai, Osaka 5998531, Japan

来源：

MACROMOLECULES | 2003年 / 36卷 / 07期

关键词：

D O I：

10.1021/ma025617a

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

PEG-attached PAMAM dendrimers with Cys residues were synthesized. It was found that the dendrimers exhibit environment-sensitive associating property against rose bengal. The network structure formed by disulfide linkages of the Cys residues at the periphery of the drimer acted as an effective barrier which controls access of the small molecules into the dendrimer interior.

引用

页码：2183 / 2186

页数：4

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