CD8 and B cell memory: same strategy, same signals

被引:26
作者
Tanchot, C [1 ]
Rocha, B [1 ]
机构
[1] Inst Necker, INSERM, U591, Paris, France
关键词
D O I
10.1038/ni0503-431
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Generation of B cell memory requires CD4(+) T cell help and involves triggering of CD40 in target B cells. Several recent studies indicate that similar signals are involved in the generation of memory CD8(+)T lymphocytes.
引用
收藏
页码:431 / 432
页数:2
相关论文
共 11 条
[1]   Help for cytotoxic-T-cell responses is mediated by CD40 signalling [J].
Bennett, SRM ;
Carbone, FR ;
Karamalis, F ;
Flavell, RA ;
Miller, JFAP ;
Heath, WR .
NATURE, 1998, 393 (6684) :478-480
[2]  
Bourgeois C, 2002, EUR J IMMUNOL, V32, P2199, DOI 10.1002/1521-4141(200208)32:8<2199::AID-IMMU2199>3.0.CO
[3]  
2-L
[4]   A role for CD40 expression on CD8+ T cells in the generation of CD8+ T cell memory [J].
Bourgeois, C ;
Rocha, B ;
Tanchot, C .
SCIENCE, 2002, 297 (5589) :2060-2063
[5]  
Gray D, 1994, Semin Immunol, V6, P303, DOI 10.1006/smim.1994.1039
[6]   Maintaining the norm: T-CELL homeostasis [J].
Jameson, SC .
NATURE REVIEWS IMMUNOLOGY, 2002, 2 (08) :547-556
[7]   CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes [J].
Janssen, EM ;
Lemmens, EE ;
Wolfe, T ;
Christen, U ;
von Herrath, MG ;
Schoenberger, SP .
NATURE, 2003, 421 (6925) :852-856
[8]   Effector and memory T-cell differentiation: Implications for vaccine development [J].
Kaech, SM ;
Wherry, EJ ;
Ahmed, R .
NATURE REVIEWS IMMUNOLOGY, 2002, 2 (04) :251-262
[9]   A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell [J].
Ridge, JP ;
Di Rosa, F ;
Matzinger, P .
NATURE, 1998, 393 (6684) :474-478
[10]   T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions [J].
Schoenberger, SP ;
Toes, REM ;
van der Voort, EIH ;
Offringa, R ;
Melief, CJM .
NATURE, 1998, 393 (6684) :480-483