Synthesis of a highly hydrophobic dimeric Lewis X containing glycolipid:: A model for the study of homotypic carbohydrate-carbohydrate interaction

被引：13

作者：

Bregant, S ^{[1
]}

Zhang, YM ^{[1
]}

Mallet, JM ^{[1
]}

Brodzki, A ^{[1
]}

Sinaÿ, P ^{[1
]}

机构：

[1] Ecole Normale Super, Dept Chim, CNRS UMR 8642, F-75231 Paris 05, France

来源：

GLYCOCONJUGATE JOURNAL | 1999年 / 16卷 / 12期

关键词：

Lewis X; glycosylation; thioglycoside; octasaccharide; carbohydrate-carbohydrate interaction;

D O I：

10.1023/A:1007115528216

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This paper describes the synthesis of an octasaccharidic glycolipid 1 based on a stereo- and regioselective glycosylation between a Lewis X trisaccharidic donor and a pentasaccharidic acceptor. A highly hydrophobic lipid moiety of a new type was selected, making the compound 1 a good candidate for the study of the interaction of Lewis X functionalised vesicles.

引用

页码：757 / 765

页数：9

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