A ribosomal protein gene cluster is encoded in the mitochondrial DNA of Dictyostelium discoideum:: UGA termination codons and similarity of gene order to Acanthamoeba castellanii

被引：18

作者：

Iwamoto, M ^{[1
]}

Pi, M ^{[1
]}

Kurihara, M ^{[1
]}

Morio, T ^{[1
]}

Tanaka, Y ^{[1
]}

机构：

[1] Univ Tsukuba, Inst Biol Sci, Tsukuba, Ibaraki 305, Japan

来源：

CURRENT GENETICS | 1998年 / 33卷 / 04期

关键词：

Dictyostelium discoideum; ribosomal protein gene; mitochondrial DNA; gene cluster;

D O I：

10.1007/s002940050341

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We sequenced a region of about 14.5 kb downstream from the ribosomal protein L11 gene (rp111) in the mitochondrial DNA (54+/-2 kb) of the cellular slime mold Dictyostelium discoideum. Sequence analysis revealed that eleven ribosomal protein genes and six open reading frames (ORFs) formed a cluster arranged in the order: rp111-orf189-rps12-rps7-rp12-rps19-orf425-orf1740-rp116-rp114-orf188-rps14-rps8-rp16-rps13-orf127-orf796. This order was very similar to that of homologous genes in Acanthamoeba castellanii mitochondrial DNA. The N-terminal region of ORF425 and the C-terminal region of ORF1740 had partial similarities to the S3 ribosomal protein of other organisms. The termination codons of rp116 and orf188 were UGA, which has not hitherto been found in genes encoded in D. discoideum mitochondrial DNA.

引用

页码：304 / 310

页数：7

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