Hydroxyurea treatment for chronic myeloid leukemia during pregnancy

被引：45

作者：

Celiloglu, M ^{[1
]}

Altunyurt, S ^{[1
]}

Undar, B ^{[1
]}

机构：

[1] Dokuz Eylul Univ, Tip Fak Hastanesi, Dept Obstet & Gynecol, Kadin Hastaliklari Dogum ABD, TR-35340 Izmir, Turkey

来源：

ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA | 2000年 / 79卷 / 09期

关键词：

chronic myeloid leukemia; hydroxurea treatment; white blood cell count;

D O I：

10.1034/j.1600-0412.2000.079009803.x

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The incidence of chronic myeloid leukemia (CML) associated with pregnancy is estimated to be 1/75,000. Several types of treatments have been used for CML during pregnancy. These are cytotoxic drugs, alpha-interferone, splenic irradiation (with shielding of the uterus) and leukapheresis. Hydroxyurea is a cytotoxic drug that inhibits the synthesis of DNA and can be used both in the chronic and accelerated phases of CML (1). We present a woman with CML who has successfully given birth to a live baby after treatment with hydroxyurea.

引用

页码：803 / 804

页数：2

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