Commentary -: Ribonucleotide reductase inhibition -: Regulation of the radiosensitive phenotype via NFκB and Bcl-2

被引：2

作者：

Dent, P ^{[1
]}

机构：

[1] Virginia Commonwealth Univ, Dept Radiat Oncol, Richmond, VA 23298 USA

来源：

CANCER BIOLOGY & THERAPY | 2002年 / 1卷 / 05期

关键词：

ribonucleotide; reductase; radiation; NF kappa B; Bcl-2; radiosensitivity;

D O I：

10.4161/cbt.1.5.175

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：546 / 547

页数：2

共 24 条

[1] Modulation of ara-CTP levels by fludarabine and hydroxyurea in leukemic cells [J].

Ahlmann, M ;

Lanvers, C ;

Lümkemann, K ;

Rössig, C ;

Freund, A ;

Baumann, M ;

Boos, J .

LEUKEMIA, 2001, 15 (01) :69-73

[2]

Bubendorf L, 1996, AM J PATHOL, V148, P1557

[3] Hydroxyurea inhibits the transactivation of the HIV-long-terminal repeat (LTR) promoter [J].

Calzado, MA ;

Macho, A ;

Lucena, C ;

Muñoz, E .

CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2000, 120 (02) :317-323

[4]

Chen XF, 2002, CANCER RES, V62, P1213

[5] Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone; 3-AP), an inhibitor of ribonucleotide reductase with antineoplastic activity [J].

Finch, RA ;

Liu, MC ;

Cory, AH ;

Cory, JG ;

Sartorelli, AC .

ADVANCES IN ENZYME REGULATION, VOL 39, 1999, 39 :3-12

[6] In vivo veritas:: Bcl-2 and Bcl-XL mediate tumor cell resistance to chemotherapy [J].

Fujita, N ;

Tsuruo, T .

DRUG RESISTANCE UPDATES, 2000, 3 (03) :149-154

[7] Role of antimetabolites of purine and pyrimidine nucleotide metabolism in tumor cell differentiation [J].

Hatse, S ;

De Clercq, E ;

Balzarini, J .

BIOCHEMICAL PHARMACOLOGY, 1999, 58 (04) :539-555

[8] NF-κB activates Bcl-2 expression in t(14;18) lymphoma cells [J].

Heckman, CA ;

Mehew, JW ;

Boxer, LM .

ONCOGENE, 2002, 21 (24) :3898-3908

[9] A recombinant adenovirus expressing wild-type Bax induces apoptosis in prostate cancer cells independently [J].

Honda, T ;

Kagawa, S ;

Spurgers, KB ;

Gjertsen, BT ;

Roth, JA ;

Fang, BL ;

Lowe, SL ;

Norris, JS ;

Meyn, RE ;

McDonnell, TJ .

CANCER BIOLOGY & THERAPY, 2002, 1 (02) :163-167

[10] Didox (A novel ribonucleotide reductase inhibitor) overcomes bcl-2 mediated radiation resistance in prostate cancer cell line PC-3 [J].

Inayat, MS ;

Chendil, D ;

Mohiuddin, M ;

Elford, HL ;

Gallicchio, VS ;

Ahmed, MM .

CANCER BIOLOGY & THERAPY, 2002, 1 (05) :539-545

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