Polymer-supported oligosaccharide synthesis by a loading-release-reloading strategy

被引：32

作者：

Belogi, G ^{[1
]}

Zhu, T ^{[1
]}

Boons, GJ ^{[1
]}

机构：

[1] Univ Georgia, Complex Carbohydrate Res Ctr, Athens, GA 30602 USA

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 36期

关键词：

D O I：

10.1016/S0040-4039(00)01183-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new synthetic strategy for solid-supported oligosaccharide synthesis has been developed whereby a synthetic intermediate can be released from the solid support, purified and reloaded for further synthesis. Key to the success of this approach is the polymeric support polystyrylboronic acid, which allows saccharides to be loaded by heating in pyridine and released by treatment with a mixture of acetone and water. (C) 2000 Published by Elsevier Science Ltd.

引用

页码：6969 / 6972

页数：4

共 22 条

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