How to quantify iron in an aqueous or biological matrix: a technical note

被引：69

作者：

Boutry, Sebastien ^{[1
]}

Forge, Delphine ^{[1
]}

Burtea, Carmen ^{[1
]}

Mahieu, Isabelle ^{[1
]}

Murariu, Oltea ^{[1
]}

Laurent, Sophie ^{[1
]}

Elst, Luce Vander ^{[1
]}

Muller, Robert N. ^{[1
]}

机构：

[1] Univ Mons, Dept Gen Organ & Biomed Chem, NMR & Mol Imaging Lab, B-7000 Mons, Belgium

来源：

CONTRAST MEDIA & MOLECULAR IMAGING | 2009年 / 4卷 / 06期

关键词：

iron oxide nanoparticles; iron quantification; relaxometry; Perls' Prussian blue; cellular magnetic labeling; MRI; contrast agents; OXIDE NANOPARTICLES; CONTRAST AGENTS; CELLS; ASSAY;

D O I：

10.1002/cmmi.291

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Iron oxide (nano)particles are powerful contrast agents for MRI and tags for magnetic cellular labeling. The need for quantitative methods to evaluate the iron content of contrast media solutions and biological matrixes is thus obvious. Several convenient methods aiming at the quantification of iron from iron oxide nanoparticle-containing samples are presented. Copyright (C) 2009 John Wiley & Sons, Ltd.

引用

页码：299 / 304

页数：6

共 16 条

[1] Molecular magnetic resonance imaging with targeted contrast agents [J].

Artemov, D .

JOURNAL OF CELLULAR BIOCHEMISTRY, 2003, 90 (03) :518-524

[2] Magnetic labeling of non-phagocytic adherent cells with iron oxide nanoparticles: a comprehensive study [J].

Boutry, Sebastien ;

Brunin, Stephanie ;

Mahieu, Isabelle ;

Laurent, Sophie ;

Elst, Luce Vander ;

Muller, Robert N. .

CONTRAST MEDIA & MOLECULAR IMAGING, 2008, 3 (06) :223-232

[3] C-MALISA (cellular magnetic-linked immunosorbent assay), a new application of cellular ELISA for MRI [J].

Burtea, C ;

Laurent, S ;

Roch, A ;

Vander Elst, L ;

Muller, RN .

JOURNAL OF INORGANIC BIOCHEMISTRY, 2005, 99 (05) :1135-1144

[4]

Christian G.D., 2003, ANAL CHEM, V6th

[5]

FORGE D, 2010, DEV MAGNETIC C UNPUB

[6]

Huheey J. E., 2006, Inorganic chemistry: principles of structure and reactivity

[7] Optimization and Validation of FePro Cell Labeling Method [J].

Janic, Branislava ;

Rad, Ali M. ;

Jordan, Elaine K. ;

Iskander, A. S. M. ;

Ali, Md M. ;

Varma, N. Ravi S. ;

Frank, Joseph A. ;

Arbab, Ali S. .

PLOS ONE, 2009, 4 (06)

[8] Chemical sensors and biosensors based on Prussian blues [J].

Koncki, R .

CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY, 2002, 32 (01) :79-96

[9] Magnetic iron oxide nanoparticles: Synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications [J].

Laurent, Sophie ;

Forge, Delphine ;

Port, Marc ;

Roch, Alain ;

Robic, Caroline ;

Elst, Luce Vander ;

Muller, Robert N. .

CHEMICAL REVIEWS, 2008, 108 (06) :2064-2110

[10]

Modo M, 2005, MOL IMAGING, V4, P143

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