Effectiveness of 50% nitrous oxide/50% oxygen during laceration repair in children

被引:64
作者
Burton, JH
Auble, TE
Fuchs, SM
机构
[1] Maine Med Ctr, Dept Emergency Med, Portland, ME 04102 USA
[2] Univ Pittsburgh, Sch Med, Pittsburgh, PA USA
[3] Dept Emergency Med, Chicago, IL USA
[4] Childrens Mem Med Ctr, Chicago, IL USA
关键词
nitrous oxide; analgesia; pediatric sedation; anxiety; laceration; wound; emergency department;
D O I
10.1111/j.1553-2712.1998.tb02594.x
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Objective: To determine, the effect of an inhaled 50% nitrous oxide/50% oxygen mixture on measures of observed anxiety in children during laceration repair. Methods: A prospective, randomized, placebo-controlled, double-blind comparison of an inhaled 50% nitrous oxide/50% oxygen mixture (treatment group) with 100% oxygen (control group) during repair of lacerations was performed, The study population was a convenience sample of children aged 2-7 years in an urban pediatric ED. The primary outcome variable was the change in scores before and during laceration repair with a 10-point modified Children's Hospital of Eastern Ontario Pain Scale (CHEOPS) assessment. The secondary outcome variable was a 4-point anxiety scale measured before and during the procedure. Results: Thirty patients were entered into the study, Seventeen children inhaled the 50% nitrous oxide/oxygen mixture and 13 inhaled 100% oxygen during laceration repair, There was no statistically significant difference in initial CHEOPS and anxiety scores between the 2 groups (p = 0.687 and 0.809, respectively). The median CHEOPS scores in the treatment group decreased by 5 points, while those of the control patients increased by 3 (p < 0.001). The median anxiety scores in the treatment population decreased by 1 paint, with an increase of 1 for the control patients (p < 0.001). Conclusion: Administration of a 50% nitrous oxide/50% oxygen mixture to children during their laceration repair resulted in a significant decrease in measures of anxiety when compared with inhalation of 100% oxygen.
引用
收藏
页码:112 / 117
页数:6
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