Granuloma annulare and malignant neoplasms

被引:56
作者
Li, AL
Hogan, DJ
Sanusi, ID
Smoller, BR
机构
[1] Louisiana State Univ, Hlth Sci Ctr, Dept Pathol, Shreveport, LA 71130 USA
[2] Louisiana State Univ, Hlth Sci Ctr, Dermatol Sect, Dept Med, Shreveport, LA 71130 USA
[3] Univ Arkansas Med Sci, Dept Pathol, Little Rock, AR 72205 USA
[4] Univ Arkansas Med Sci, Dept Dermatol, Little Rock, AR 72205 USA
关键词
granuloma annulare; malignant neoplasm; lymphoma;
D O I
10.1097/00000372-200304000-00004
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 [皮肤病与性病学];
摘要
The relationship between granuloma annulare (GA) and malignant neoplasms is uncertain. Several case reports and clinical correlation studies have addressed this issue; however no review articles have summarized those reported cases an statistically analyzed the association. Fourteen case reports and two correlation studies directly addressing the relationship of GA and malignant neoplasms were found from the Medline database from 1966-2001. A total of 16 cases from case reports were available with the mean age of 54. Most of the GA patients had an atypical clinical presentation. The time between the onset of GA and the discovery of the malignant neoplasms varied from 18 months before (median = 5 months) to 7 years after (median = 42 months). More than half of those cases were associated with lymphoma. No definite relationship was found between GA and malignant neoplasms. Older patients with skin lesions not clinically typical of GA but that histologically resemble classic GA, may be considered for investigation of underlying malignant lymphoma or other malignancies.
引用
收藏
页码:113 / 116
页数:4
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