Late-onset optic pathway tumors in children with neurofibromatosis 1

被引：84

作者：

Listernick, R

Ferner, RE

Piersall, L

Sharif, S

Gutmann, DH

Charrow, J

机构：

[1] Childrens Mem Hosp, Div Gen Acad Pediat, Chicago, IL 60614 USA

[2] Childrens Mem Hosp, Div Genet, Chicago, IL 60614 USA

[3] Northwestern Univ, Feinberg Sch Med, Dept Pediat, Chicago, IL 60611 USA

[4] Washington Univ, Sch Med, Dept Pediat, St Louis, MO 63110 USA

[5] Washington Univ, Sch Med, Dept Neurol, St Louis, MO 63110 USA

[6] Guys Kings & St Thomas Sch Med, Dept Clin Neurosci, London, England

[7] St Marys Hosp, Dept Med Genet, Manchester M13 0JH, Lancs, England

来源：

NEUROLOGY | 2004年 / 63卷 / 10期

关键词：

D O I：

10.1212/01.WNL.0000144341.16830.01

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Identification of new optic pathway tumors (OPTs) and progression of pre-existing OPTs in children with neurofibromatosis 1 (NF1) have been reported infrequently after age 6. The authors present eight children with NF1 ( mean age 12.2 years) seen in three NF1 centers who had either late-onset ( four of eight) or late-progressive ( seven of eight) OPT. Continued monitoring of individuals with NF1 into adulthood for the development of OPTs and for progression of known OPTs is warranted.

引用

页码：1944 / 1946

页数：3

共 9 条

[1] Visual loss in children with neurofibromatosis type 1 and optic pathway gliomas: Relation to tumor location by magnetic resonance imaging [J].