Pro-epileptic changes in synaptic function can be accompanied by pro-epileptic changes in neuronal excitability

被引：40

作者：

Wheal, HV ^{[1
]}

Bernard, C

Chad, JE

Cannon, RC

机构：

[1] Univ Southampton, Sch Biol Sci, Neurosci Res Grp, Southampton SO16 7PX, Hants, England

[2] Hop Port Royal, INSERM, U29, F-75014 Paris, France

来源：

TRENDS IN NEUROSCIENCES | 1998年 / 21卷 / 04期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/S0166-2236(97)01182-X

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Repetitive sensory input, stroboscopic lights or repeated sounds can induce epileptic seizures in susceptible individuals. In order to understand the process we have to consider multiple factors. The output of a set of neurones is determined by the amount of excitatory synaptic input, the degree of positive feedback and their inherent electrical excitability, which can be modified by synaptic inhibition. Recent research has shown that it is possible to separate these phenomena, and that they do not always behave in unison.

引用

页码：167 / 174

页数：8

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