Curation of the Plasmodium falciparum genome

被引:10
作者
Berry, AE
Gardner, MJ
Caspers, GJ
Roos, DS
Berriman, M
机构
[1] Wellcome Trust Sanger Inst, Pathogen Sequencing Unit, Cambridge CB10 1SA, England
[2] Inst Genome Res, Rockville, MD 20850 USA
[3] Radboud Univ Nijmegen, Njimegen Ctr Mol Life Sci & Biomol Informat, NL-6500 GL Nijmegen, Netherlands
[4] Univ Penn, Dept Biol, Philadelphia, PA 19104 USA
[5] Univ Penn, Genom Inst, Philadelphia, PA 19104 USA
关键词
D O I
10.1016/j.pt.2004.09.003
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
The malaria genome has proved invaluable to researchers worldwide in the continuing fight against malaria by stimulating and underpinning molecular approaches in gene expression studies, vaccine and drug discovery research, and by providing data to facilitate hypothesis-driven research. The combination of in silico and experimental investigations has already yielded dividends by strengthening our understanding of the many facets of the malaria parasite Plasmodium falciparum. The recently initiated curation of the genome resource is a vital investment for maintaining and enhancing the use of this genomic information in the post-genomic era.
引用
收藏
页码:548 / 552
页数:5
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