A functional dosage compensation complex required for male killing in Drosophila

被引：71

作者：

Veneti, Z

Bentley, JK

Koana, T

Braig, HR

Hurst, GDD

机构：

[1] UCL, Dept Biol, London NW1 2HE, England

[2] Cent Res Inst Elect Power Ind, Low Dose Radiat Res Ctr, Tokyo 2018511, Japan

[3] Univ Wales, Sch Biol Sci, Bangor LL57 2UW, Gwynedd, Wales

来源：

SCIENCE | 2005年 / 307卷 / 5714期

关键词：

D O I：

10.1126/science.1107182

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Bacteria that selectively kilt males ("male-killers") were first characterized more than 50 years ago in Drosophila and have proved to be common in insects. However, the mechanism by which sex specificity of virulence is achieved has remained unknown. We tested the ability of Spiroplasma poulsonii to kill Drosophila melanogaster mates carrying mutations in genes that encode the dosage compensation complex. The bacterium failed to kill mates lacking any of the five protein components of the complex.

引用

页码：1461 / 1463

页数：3

共 13 条

[1]

CLINE TW, 1984, GENETICS, V107, P231

[2] DEVELOPMENTAL EFFECTS OF SEX-RATIO AGENT IN EMBRYOS OF DROSOPHILA WILLISTONI [J].