Detection of endometriosis with the use of plasma protein profiling by surf ace-enhanced laser desorption/ionization time-of-flight mass spectrometry

被引:40
作者
Liu, Haiyuan
Lang, Jinghe
Zhou, Qunfang
Shan, Dan
Li, Qizhai
机构
[1] Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Obstet & Gynecol, Beijing 100730, Peoples R China
[2] Chinese Acad Sci, Acad Math & Syst Sci, Beijing 100080, Peoples R China
关键词
D O I
10.1016/j.fertnstert.2006.08.095
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
In this prospective case-control study, we determined the role of surface-enhanced laser desorption and ionization time-of-flight mass spectrometry in the detection of histologically proven endometriosis. In the plasma of the group with endometriosis, there were 20 different protein peaks, and the classifier showed a sensitivity of 87.5% and a specificity of 80% in the diagnosis of endometriosis.
引用
收藏
页码:988 / 990
页数:3
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