Tight junctions in the skin

被引:45
作者
Morita, K [1 ]
Miyachi, Y [1 ]
机构
[1] Kyoto Univ, Dept Dermatol, Grad Sch Med, Kyoto 6068507, Japan
关键词
epithelia; skin; tight junctions;
D O I
10.1016/S0923-1811(03)00038-0
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Tight junctions (= zonulae occludentes, TJs) function as an effective barrier in simple epithelia. Recent developments in the molecular biology of TJs revealed that TJs also exist in the stratum granulosum and contribute to barrier function in epidermis. Furthermore, several TJ-related junctions were identified in epidermis. In this review article, the history of the investigation into TJs in epidermis and the perspectives of investigation into TJs in dermatology are described. (C) 2003 Japanese Society for Investigative Dermatology. Published by Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:81 / 89
页数:9
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