A case of multicentric Castleman's disease associated with renal amyloidosis and pure red cell aplasia

被引：18

作者：

Funabiki, K ^{[1
]}

Kaneko, S ^{[1
]}

Terajima, M ^{[1
]}

Tomita, H ^{[1
]}

Kawano, Y ^{[1
]}

Tomino, Y ^{[1
]}

机构：

[1] Juntendo Univ, Sch Med, Dept Med, Div Nephrol, Tokyo 113, Japan

来源：

AMERICAN JOURNAL OF NEPHROLOGY | 1998年 / 18卷 / 03期

关键词：

multicentric Castleman's disease; renal amyloidosis; pure red cell aplasia; steroid therapy;

D O I：

10.1159/000013346

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

This is the first reported case of multicentric Castleman's disease (MCD) associated with renal amyloidosis and pure red cell aplasia (PRCA). Inguinal lymph node biopsy showed follicular hyperplasia with prominent germinal centers and plasma cell proliferation in the interfollicular areas. Renal biopsy specimens revealed intraglomerular amyloid deposits, defined as AA amyloidosis. Since amyloid deposits were not present in the gastric and rectal mucosal tissues, his renal disorder was found to be an unusual secondary amyloidosis associated with MCD. Following treatment by plasma exchange, there was progressive deterioration of anemia due to PRCA detected by bone marrow aspiration. Subsequently he was successfully treated with steroid pulse therapy not only for anemia but also for renal function.

引用

页码：247 / 250

页数：4

共 22 条

[1] DYSREGULATED INTERLEUKIN-6 EXPRESSION PRODUCES A SYNDROME RESEMBLING CASTLEMANS DISEASE IN MICE [J].

BRANDT, SJ ;

BODINE, DM ;

DUNBAR, CE ;

NIENHUIS, AW .

JOURNAL OF CLINICAL INVESTIGATION, 1990, 86 (02) :592-599

[2]

CASTLEMAN B, 1956, CANCER, V9, P822, DOI 10.1002/1097-0142(195607/08)9:4<822::AID-CNCR2820090430>3.0.CO

[3]

2-4

[4] PURE RED-CELL APLASIA IN PATIENTS WITH CHRONIC LYMPHOCYTIC-LEUKEMIA [J].

CHIKKAPPA, G ;

ZARRABI, MH ;

TSAN, MF .

MEDICINE, 1986, 65 (05) :339-351

[5] ANGIOFOLLICULAR AND PLASMACYTIC POLYADENOPATHY - A PSEUDO-TUMOROUS SYNDROME WITH DYSIMMUNITY [J].

DIEBOLD, J ;

TULLIEZ, M ;

BERNADOU, A ;

AUDOUIN, J ;

TRICOT, G ;

REYNES, M ;

BILSKIPASQUIER, G .

JOURNAL OF CLINICAL PATHOLOGY, 1980, 33 (11) :1068-1076

[6] A SYSTEMIC LYMPHOPROLIFERATIVE DISORDER WITH MORPHOLOGIC FEATURES OF CASTLEMANS DISEASE - CLINICAL FINDINGS AND CLINICOPATHOLOGIC CORRELATIONS IN 15 PATIENTS [J].

FRIZZERA, G ;

PETERSON, BA ;

BAYRD, ED ;

GOLDMAN, A .

JOURNAL OF CLINICAL ONCOLOGY, 1985, 3 (09) :1202-1216

[7]

GABA AR, 1978, AM J CLIN PATHOL, V69, P86

[8]

HUMPHERYS SR, 1975, MAYO CLIN PROC, V50, P317

[9] TICLOPIDINE TREATMENT IN IDIOPATHIC PLASMACYTIC LYMPHADENOPATHY WITH POLYCLONAL HYPERIMMUNOGLOBULINEMIA ACCOMPANIED BY NEPHROTIC SYNDROME [J].

KATO, Y ;

KOBAYASHI, H ;

MIHARA, H ;

MIZUTANI, Y ;

KAMIJIMA, S ;

TANAKA, A ;

TAKEDA, H ;

KATO, R ;

OGURI, T .

INTERNAL MEDICINE, 1992, 31 (04) :504-507

[10] CASTLEMAN DISEASE AND RENAL AMYLOIDOSIS [J].

KAZES, I ;

DERAY, G ;

JACOBS, C .

ANNALS OF INTERNAL MEDICINE, 1995, 122 (05) :395-396

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