Bacterial heme oxygenases

被引：81

作者：

Frankenberg-Dinkel, N ^{[1
]}

机构：

[1] Tech Univ Braunschweig, Inst Microbiol, D-38106 Braunschweig, Germany

来源：

ANTIOXIDANTS & REDOX SIGNALING | 2004年 / 6卷 / 05期

关键词：

D O I：

10.1089/1523086041798060

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The importance of heme oxygenases in heme catabolism, iron utilization, and cellular signaling has been recognized for many years and is a well studied process in eukaryotes. Through the accessibility of an increasing number of bacterial genomes, it has become evident that heme oxygenases are also widespread in prokaryotes. In these organisms, the heme oxygenase reaction serves a similar function as in eukaryotes. A major role of bacterial heme oxygenases has been attributed to acquisition of iron in prokaryotic pathogens, but other functions, such as involvement in phytobilin biosynthesis, have been described. This review summarizes the current state of the art on bacterial heme oxygenase research. The various biological roles of this enzyme in prokaryotes and their biochemical properties will be discussed.

引用

页码：825 / 834

页数：10

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