Vibrational spectroscopy as a tool for probing protein function

被引：87

作者：

Vogel, R ^{[1
]}

Siebert, F ^{[1
]}

机构：

[1] Univ Freiburg, Inst Mol Med & Zellforsch, Sekt Biophys, D-79104 Freiburg, Germany

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 2000年 / 4卷 / 05期

关键词：

D O I：

10.1016/S1367-5931(00)00125-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Vibrational spectroscopy has become increasingly important as a tool for understanding the mechanisms of photosystem II, phytochrome and terminal oxidases. More general enzymatic or receptor systems have been studied, opening a new field of applications. Femtosecond infrared pump/probe studies of the important amide-I band seem to provide a basis for its molecular and structural interpretation.

引用

页码：518 / 523

页数：6

共 61 条

[1] Probing the photoreaction mechanism of phytochrome through analysis of resonance Raman vibrational spectra of recombinant analogues [J].

Andel, F ;

Murphy, JT ;

Haas, JA ;

McDowell, MT ;

van der Hoef, I ;

Lugtenburg, J ;

Lagarias, JC ;

Mathies, RA .

BIOCHEMISTRY, 2000, 39 (10) :2667-2676

[2] Internal dynamics of the nicotinic acetylcholine receptor in reconstituted membranes [J].

Baenziger, JE ;

Darsaut, TE ;

Morris, ML .

BIOCHEMISTRY, 1999, 38 (16) :4905-4911

[3] Effect of membrane lipid composition on the conformational equilibria of the nicotinic acetylcholine receptor [J].

Baenziger, JE ;

Morris, ML ;

Darsaut, TE ;

Ryan, SE .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (02) :777-784

[4] Phosphoenzyme conversion of the sarcoplasmic reticulum Ca2+-ATPase -: Molecular interpretation of infrared difference spectra [J].

Barth, A .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (32) :22170-22175

[5] Functional properties of the heme propionates in cytochrome c oxidase from Paracoccus denitrificans.: Evidence from FTIR difference spectroscopy and site-directed mutagenesis [J].

Behr, J ;

Michel, H ;

Mäntele, W ;

Hellwig, P .

BIOCHEMISTRY, 2000, 39 (06) :1356-1363

[6] Light-induced FTIR difference spectroscopy of photosynthetic charge separation between 9000 and 250cm-1 [J].

Breton, J ;

Nabedryk, E ;

Clérici, A .

VIBRATIONAL SPECTROSCOPY, 1999, 19 (01) :71-75

[7] Conformational heterogeneity of the bacteriopheophytin electron acceptor HA in reaction centers from Rhodopseudomonas viridis revealed by Fourier transform infrared spectroscopy and site-directed mutagenesis [J].

Breton, J ;

Bibikova, M ;

Oesterhelt, D ;

Nabedryk, E .

BIOCHEMISTRY, 1999, 38 (35) :11541-11552

[8] FTIR study of the primary electron donor of photosystem I (P700) revealing delocalization of the charge in P700+ and localization of the triplet character in 3P700 [J].

Breton, J ;

Nabedryk, E ;

Leibl, W .

BIOCHEMISTRY, 1999, 38 (36) :11585-11592

[9] Raman spectroscopy, the sleeping giant in structural biology, awakes [J].

Carey, PR .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (38) :26625-26628

[10] Hydrogen bonding and protein perturbation in β-lactam acyl-enzymes of Streptococcus pneumoniae penicillin-binding protein PBP2x [J].

Chittock, RS ;

Ward, S ;

Wilkinson, AS ;

Caspers, P ;

Mensch, B ;

Page, MGP ;

Wharton, CW .

BIOCHEMICAL JOURNAL, 1999, 338 :153-159

← 1 2 3 4 5 6 7 →