Tumor necrosis factor receptor associated factor 4 (TRAF4) expression pattern during mouse development

被引：42

作者：

Masson, R

Régnier, CH

Chenard, MP

Wendling, C

Mattei, MG

Tomasetto, C

Rio, MC

机构：

[1] ULP, Inst Genet & Biol Mol & Cellulaire, CNRS, INSERM,U184, F-67404 Illkirch, CU Strasbourg, France

[2] CHU Hautepierre, Serv Anat Pathol Gen, F-67098 Strasbourg, France

[3] Fac Med Timone, F-13385 Marseille, France

[4] INSERM, U406, F-13258 Marseille, France

来源：

MECHANISMS OF DEVELOPMENT | 1998年 / 71卷 / 1-2期

基金：

澳大利亚研究理事会;

关键词：

mouse TRAF4 cDNA cloning; development; neurogenesis; adult brain; TNF receptor associated factor 1; TNF receptor associated factor 2; TNF receptor associated factor 3; TNF receptor associated factor 4; cysteine-rich motif associated with RING and TRAF domains (CART1); tumor necrosis factor; in situ hybridization; northern blot; bromodeoxyuridine (BrdU); class III beta-tubulin; mouse chromosome 11; syntenic linkage conservation;

D O I：

10.1016/S0925-4773(97)00192-5

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

This is the first in situ hybridization analysis of expression of a tumor necrosis factor (TNF) receptor associated factor (TRAF) during development. TRAF4 is observed throughout mouse embryogenesis, most notably during ontogenesis of the central (CNS) and peripheral (PNS) nervous system, and of nervous tissues of sensory organs. TRAF4 is preferentially expressed by post-mitotic undifferentiated neurons. Interestingly, TRAF4 remains expressed in the adult hippocampus and olfactory bulb, known to contain multipotential cells responsible for neoneurogenesis. (C) 1998 Elsevier Science Ireland Ltd.

引用

页码：187 / 191

页数：5

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