Diffusion tensor imaging in normal aging and neuropsychiatric disorders

被引：119

作者：

Sullivan, EV

Pfefferbaum, A

机构：

[1] SRI Int, Hlth Sci Ctr, Neurosci Program, Menlo Pk, CA 94025 USA

[2] Stanford Univ, Sch Med, Dept Psychiat & Behav Sci, Stanford, CA 94305 USA

来源：

EUROPEAN JOURNAL OF RADIOLOGY | 2003年 / 45卷 / 03期

关键词：

diffusion imaging; aging; psychiatric disorder; neurological disorder; white matter; anisotropy; ditfusivity;

D O I：

10.1016/S0720-048X(02)00313-3

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The application of diffusion imaging to the quantitative study of the effects of normal aging and neuropsychiatric diseases on brain tissue microstructure has witnessed its greatest development just over the last few years. Measures derived from diffusion imaging have already been shown to have great utility in identifying age- and disease-related degradation of regional microstructure, particularly of white matter. Investigations comparing diagnoses hold promise for contribution to differential diagnosis. Correlations with cognitive and motor performance provide evidence for functional ramifications of these diffusion measures. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：244 / 255

页数：12

共 144 条

[1] Normal aging in the central nervous system: quantitative MR diffusion-tensor analysis [J].